TABLE 2.Fast and slow inactivating components of 4-AP–sensitive Ka currents in control and CCD neurons
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Control | CCD | |
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Ifast (pA/pF) | 53.0 ± 6.8 | 30.4 ± 4.3* |
τfast (ms) | 12.89 ± 2.12 | 10.46 ± 1.28 |
Islow (pA/pF) | 16.3 ± 3.9 | 16.7 ± 3.2 |
τslow (ms) | 130.7 ± 21.5 | 91.3 ± 9.8 |
n | 15 | 15 |
Values are mean ± SE A two-term exponential function was used to fit the falling phase of 4-AP–sensitive Ka currents. The current amplitude (Ifast and Islow) and time constant (τfast and τslow) for each cell were determined.
* P < 0.01 (Student's t-test; significant difference between control and CCD).